Fascination About Wockhardt Promethazine with Codeine Oral Solution
Fascination About Wockhardt Promethazine with Codeine Oral Solution
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are pregnant or strategy to become pregnant. PROMETHAZINE WITH CODEINE ORAL SOLUTION can damage your unborn baby. See “What's The most crucial info I should understand about PROMETHAZINE WITH CODEINE ORAL SOLUTION?” are breastfeeding or intend to breastfeed. Codeine passes into your breast milk and could potentially cause significant Uncomfortable side effects in your child which includes greater sleepiness, respiratory difficulties (respiratory melancholy), and death. It is not known if promethazine can go into your breast milk.
The concomitant use of Promethazine HCl and Codeine Phosphate Oral Solution with all cytochrome P450 3A4 inducers or discontinuation of the cytochrome P450 3A4 inhibitor may well end in decreased codeine stages, increased norcodeine amounts, and less metabolism via 2D6 with resultant lower morphine concentrations.
When useful for an extended time, this medication may not operate too and will require various dosing. Discuss with your doctor if this medication stops Performing nicely.
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If your response to an opioid antagonist is suboptimal or only temporary in mother nature, administer added antagonist as directed with the product or service’s prescribing facts. The respiratory depressant results of promethazine usually are not reversed by opioid antagonists, which include naloxone.
Steer clear of concurrent here use of Promethazine with Codeine Oral Solution with alcohol or other central anxious process depressants simply because additional impairment of central nervous program efficiency may possibly arise [see Warnings and Precautions ( 5.ten) ].
This medication could make you additional delicate for the Sunlight. Limit your time and energy from the Sunlight. Stay away from tanning booths and sunlamps. Use sunscreen and wear protecting clothes when outdoor. Inform your physician right away if you obtain sunburned or have skin blisters/redness.
Labor or Delivery Opioids cross the placenta and could produce respiratory depression and psycho-physiologic outcomes in neonates. An opioid antagonist, for example naloxone, must be readily available for reversal of opioid-induced respiratory depression from the neonate. Opioids, such as Promethazine with Codeine Oral Solution, can extend labor through steps which temporarily lessen the strength, duration, and frequency of uterine contractions.
It can be soluble in water and freely soluble in Liquor. The molecular weight is 320.88. Its molecular formulation is C 17H 20N 2S • HCl, and it's the subsequent chemical composition.
Labor or Supply Opioids cross the placenta and could create respiratory despair and psycho-physiologic consequences in neonates. An opioid antagonist, including naloxone, has to be readily available for reversal of opioid-induced respiratory depression inside the neonate.
Position the combination in a very container like a sealed plastic bag and toss it absent while in the home trash. You can also follow your point out or community tips on how to safely toss away Promethazine Hydrochloride and Codeine Phosphate Oral Solution.
Keep at place temperature faraway from gentle and dampness. Tend not to retailer in the toilet. Preserve all prescription drugs faraway from young children and pets.
Make sure sufferers have an oral dosing dispenser that steps the suitable volume in milliliters. Counsel clients on how to utilize an oral dosing dispenser and correctly evaluate the oral suspension as prescribed.
Promethazine with Codeine Oral Solution really should be applied with warning in sufferers with bone-marrow depression. Leukopenia and agranulocytosis have already been documented, commonly when promethazine has long been Employed in Affiliation with other known marrow-toxic agents.